With the release of the Android 4.0 SDK it is possible to play with Google's support for Exchange ActiveSync which is included with the Android SDK emulator package.
It is important to note that just because the build of Android supports it, it is down to individual device manufacturers as to whether they choose to implement Exchange support, or they may choose to develop their own, superior, Exchange email client software.
This post is for geek interest only.

HTC and Motorola-based Android devices do feature their own Exchange email client developed by the manufacturer.

For instructions on how to configure the Android SDK on MacOS, read this article - http://blog.brightpointuk.co.uk/running-android-sdk-mac-os-106-snow-leopard

Setting up the Exchange account

The Email client is located in the Apps section of the launcher:

Launching the email client for the first time will prompt you to enter your email address and password:

The client will attempt to determine the correct settings to use based on the email address entered. If the client cannot determine these settings automatically you will be prompted to specify the type of account you are trying to configure:

Select Exchange:

You will be prompted to enter in your Exchange username in the form "Domain\Username".
You will be able to obtain this information from your IT department if you do not know it, but as a rule the domain will be the contents of the "Log Into" field on your desktop or laptop when you log into it - if you have one. The username will be the same as that used to access your PC, as will the password.
Note that the client will fill in the username for you based on the email address entered - it may not necessarily be correct, check it carefully.

You will also need to enter the Server Address, part of which will be filled in for you. Again this information can be obtained from your IT department, but if you access your email via a web browser using Outlook Web Access, then the server address will be the same as that entered into the browser, normally in the form "mail.company.com"

Finally you'll need to specify whether the connection should use SSL or not - as a rule this will be enabled.

Once all fields have been completed, tap Next. You will be receive notification that by setting up an Exchange email account, you are accepting that the administrator of the Exchange server has the ability to remotely wipe your device should the company deem it necessary to do so:

Tap OK to continue configuring the account. On the next screen you can specify which mailbox folders you wish to synhronise, and how often:

Tap Next to continue. You will receive a message in the notification area prompting you that security settings have changed and need acknowledging:

The features that the Exchange ActiveSync policy will be able to enforce on your device will be listed

Tap Activate to acknowledge the new security policy. You will be returned to the email setup wizard and be prompted to enter a name to identify the email account, this can be anything meaningful to you:

Once complete you will be taken to the email inbox:

When composing new email messages, suggestions from the Global Address List and contacts will be displayed as you start to type in the name of a recipient:

Mailbox folders can be navigated between:

To adjust email account settings once they have been entered, launch Settings from the app launcher:

And select Accounts & Sync

Select the entry for the email account

Enable or disable synchronisation items:

Select Account Settings to adjust general settings governing all email accounts as well as specific account settings

General settings allow you to define such actions as which email is displayed immediately after another email is deleted:

Select the specific email account to adjust synchronisation settings for that account

To review the Device Administrator settings, or deactivate a device administrator, select Security from the Settings menu followed by Device Administrators

Select the Email account

Enforced policies will be displayed: